PDRN Healer 婴儿针 is a skin healing treatment available in the market formulated to improve ageing skin while stimulating the growth of new collagen by re-activating the skin’s ability to restore its own collagen structure and skin elasticity. 

What is it made of?

The main ingredient of PDRN Skin Healer apart is c-PDRN, which stands for Cosmetic PolyDeoxyRiboNuceotide and it is a DNA component of wild salmon that promotes skin improvement and regeneration. [1]

The salmon DNA has the most biocompatible composition to human skin — making it safer, stable and has the least risk of an adverse immune response. Rest assured, it is purified and processed for medical use. 

This helps provide hydration and remove wrinkles, promotes skin regeneration and, hence, greatly reduces ageing effects. 

What does PDRN Healer do?

The main properties and benefits of PDRN Healer are:

Physicochemical properties include:

• Hydration effect
• Scaffolding effect (Dermis replacement)
• Long-lasting effect

Biological properties include:

• Epidermis/Dermis regeneration
• Collagen/Non-collagen protein secretion
• ECM restoration

Main Effects of PDRN:

• Anti-ageing
• Excellent skin regeneration effects
• Improved skin texture
• Regulates sebum secretion and improves skin hydration levels
• Proven for safety with no adverse reactions
• Quick visible results

How is PDRN Healer administered?

PDRN healer is delivered into the dermis through an injection technique called microneedling, which has skin healing and anti-ageing purposes. 

• Wound healing – through stimulation of skin healing growth, increased microcirculation and hydration elements.
• Anti-inflammatory effects – through the clearing of free radicals and blockage of inflammatory cytokines in the body.

This involves the use of ultra-fine microneedles, with minimal to no pain and less bruising compared to other treatments.

Where can it be used and who can use it?

Suitable treatment areas for PDRN Healer:

• Around the eyes
• Under the eyes
• Cheeks
• Around the jawline

Suitable Candidates for PDRN Skin Healer:

• Those seeking long-lasting skin renewal and healing
• Those who wish to restore the skin’s balance of oil and moisture
• Have large pores and want to improve the skin's texture
• Treat wrinkles around the eyes area, smile lines and forehead, and want to improve aged skin
• Looking for a more natural alternative to treat wrinkles around the eyes/mouth/forehead wrinkles

What is the healing process like?

Here’s a brief timeline of the post-treatment healing process:

After 2-5 days

Patients observe smoother skin texture, clearer complexion and improved oil balance and less sebum production

After 2 to 4 weeks

Patients observe increased skin elasticity through the regeneration of naturally produced collagen. There is a general improvement in the appearance of the eyes and face. Patients’ pores are reduced in size.

After 4 to 6 weeks

Patients notice an improved appearance to the overall appearance of skin, which looks healthier, brighter and firmer.

There is minimal to no downtime for PDRN Healer treatment. However, some patients may experience slight swelling and redness around the treatment areas, which usually resolves naturally within 24 hours.

What results can I expect from PDRN Healer?

PDRN Healer is very safe as its components are biocompatible with our body. After just a month of regular and consistent treatment, about 15% of patients reported a huge improvement in skin hydration and about 22% of patients recognised improvements in terms of skin elasticity.

While results from the treatment may often be noticed after around 1-3 treatments, a total of 3 sessions are recommended at an interval of 3 weeks. However, it would be important to note that effects are also dependent on the patient’s skin condition, skin type and may be influenced by external factors such as frequency and intensity of exercise, diet and stress levels.

During the stage of post-treatment, regular patients may expect to observe progressive improvements with the final results showing up between 4 to 6 weeks.

1. Pak, C. S., Lee, J., Lee, H., Jeong, J., Kim, E. H., Jeong, J., Choi, H., Kim, B., Oh, S., Kim, I., & Heo, C. Y. (2014). A phase III, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow's feet: a new concept of regenerative filler. Journal of Korean medical science, 29 Suppl 3(Suppl 3), S201–S209. https://doi.org/10.3346/jkms.2014.29.S3.S201 (Retraction published J Korean Med Sci. 2016 Feb;31(2):330)